Trypanosomosis in dogs can possess an acute or chronic course of disease. The acute course is mainly characterised by fever, a rapidly deteriorating general condition with anaemia, leucopenia, thrombocytopenia, circular and respiratory symptoms, multiple bleeding and oedema, conjunctivitis and opacity of the cornea. Except from Trypanosoma congolense infection, central nervous symptoms due to a meningoencephalomyelitis can also occur. In such cases, death will follow within days. In general, infection by T. cruzi is usually benign, but some dogs might present fever during the first weeks post infection and chronic myocarditis.