Sometimes the organism can be detected in a blood smear in its typical location inside the cell. But the number of pathogens in the peripheral blood can fluctuate massively, so that blood smear examination can be false negative up to 50% of the time. Due to the high sensitivity of PCR assays, these tests are the method of choice for Mycoplasma diagnostic in dogs. Real-time PCR to quantify hemoplasma DNA has been developed and can be used to monitor response to treatment. The PCR blood test to detect hemotropic mycoplasms is commercially available.
- Lappin MR: Bartonella and Haemobartonella in cats and dogs: Current knowledge. In: The Bayer 7th Int. Parasite Symp., 2006, Proc. BSAVA Pre-Congress Symp., Birmingham, pp 17-25
- Messick JB: New perspectives about Hemotrophic mycoplasma (formerly, Haemobartonella and Eperythrozoon species) infections in dogs and cats. Vet Clin North Am Small Anim Pract. 2003, 33, 1453-65