Treatment and Prevention
There is no consistent treatment protocol for Bartonella vinsonii subsp. berkhoffii infection in dogs.
Antibiotic treatment should be performed with an antibiotic capable of crossing lipid membranes and reaching high intracellular concentrations, as azithromycin, doxycycline, and enrofloxacin. Macrolides, like azithromycin are effective, but B. henselae isolates rapidly develop resistance. Treatment of several weeks duration may be needed to eliminate Bartonella spp. infections.
Dogs should be protected from flea and tick infestations by the regular use of acaricides in the form of collars, spot-on or spray-on formulations. Vaccines against B. henselae and B. vinsonii subsp. berkhoffii are not available.
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